Citric acid-13C6 is the 13C-labeled Citric acid (HY-N1428). Citric acid is a natural preservative and food tartness enhancer. It has been shown to induce apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Additionally, citric acid can cause oxidative damage of the liver by decreasing antioxidative enzyme activities. It is also utilized as an acidulant, emulsifier, sequestrant, and buffering agent across various industries.
- Used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes have been incorporated into drug molecules for quantitation during drug development.
- Deuteration can potentially affect the pharmacokinetic and metabolic profiles of drugs.